
HSE Scientists Uncover Mechanism Behind Placental Lipid Metabolism Disorders in Preeclampsia
Scientists at HSE University have discovered that in preeclampsia—one of the most severe complications of pregnancy—the placenta remodels its lipid metabolism, reducing its own cholesterol synthesis while increasing cholesterol transfer to the foetus. This compensatory mechanism helps sustain foetal nutrition but accelerates placental deterioration and may lead to preterm birth. The study findings have been published in Frontiers in Molecular Biosciences.


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